Erythrocyte deformation under shear flow.
نویسنده
چکیده
منابع مشابه
Detect of Sublethal Damage with Cyclic Deformation of Erythrocyte in Shear Flow
The deformation of an erythrocyte has been observed microscopically in the shear flow to detect the sublethal damage of an erythrocyte in vitro. A rheoscope system has been manufactured to observe the deformation of the suspended erythrocytes in the shear flow. The rheoscope consists of a pair of parallel disks and an inverted phasecontrast microscope. The human erythrocytes were suspended in t...
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A novel apparatus for detecting a subtle decrease in erythrocyte deformability was developed. The oscillatory shape change of erythrocytes was monitored under an oscillatory shear stress (modulating the oscillation frequency in the range of 9-90 dyn/cm2). The ellipsoidal deformation of intact erythrocytes perfectly followed the oscillatory force of up to about 2 Hz, but the diamide-treated cell...
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The effect of shear force (depending on shear rate and viscosity of extracellular medium) and hematocrit of RBC suspension on RBC deformation was studied quantitatively using a cone-plate rheoscope with various kinds of cells, ie, partially hemolyzed (PH) cells, density-fractionated intact cells, and diamide-treated cells. The deformation index (DI) of ellipsoidally deformed cells was shown to ...
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Hemolysis is caused by fluid stresses in flows within hypodermic needles, blood pumps, artificial hearts, and other cardiovascular devices. Developers of cardiovascular devices may expend considerable time and effort in testing of prototypes, because there is currently insufficient understanding of how flow-induced cell damage occurs to accurately predict hemolysis. The objective of this projec...
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عنوان ژورنال:
- Blood
دوره 73 4 شماره
صفحات -
تاریخ انتشار 1989